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Journal of Neurorestoratology  2021, Vol. 9 Issue (1): 1-12    doi: 10.26599/JNR.2021.9040002
Review Article     
The 2020 Yearbook of Neurorestoratology
Hongyun Huang1,(✉)(),Lin Chen2,Michael Chopp3,4,Wise Young5,John Robert Bach6,Xijing He7,Anna Sarnowaska8,Mengzhou Xue9,Robert Chunhua Zhao10,Ashok Shetty11,Dario Siniscalco12,Xiaoling Guo13,Alireza Khoshnevisan14,Ziad Hawamdeh15
1Beijing Hongtianji Neuroscience Academy, Beijing 100143, China
2Department of Neurosurgery, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine Beijing, Beijing 100007, China
3Department of Neurology, Henry Ford Hospital, Detroit, MI, USA
4Department of Physics, Oakland University, Rochester, MI, USA
5Department of Cell Biochemistry and Neuroscience, Rutgers University, New Jersey, USA
6Center for Ventilator Management Alternatives, University Hospital, Newark, New Jersey, USA
7Department of Orthopedics, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi, China
8Translational Platform for Regenerative Medicine & Cell Therapy Team of The Central Nervous System Diseases, Polish Academy of Sciences, Warsaw, Poland
9The Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Henan Joint International Laboratory of Intracerebral Hemorrhagic Brain Injury, Zhengzhou 450001, Henan, China
10Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy, Beijing 100005, China
11Institute for Regenerative Medicine, Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M University, USA
12Department of Experimental Medicine, University of Campania "Luigi Vanvitelli" via S. Maria di Costantinopoli 16 80138 Naples, Italy
13Neurological Center, The 981 Hospital of PLA, Chengde 067000, Hebei, China
14School of Medicine, The University of Jordan, Amman, Jordan
15Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran
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COVID-19 has been an emerging and rapidly evolving risk to people of the world in 2020. Facing this dangerous situation, many colleagues in Neurorestoratology did their best to avoid infection if themselves and their patients, and continued their work in the research areas described in the 2020 Yearbook of Neurorestoratology. Neurorestorative achievements and progress during 2020 includes recent findings on the pathogenesis of neurological diseases, neurorestorative mechanisms and clinical therapeutic achievements. Therapeutic progress during this year included advances in cell therapies, neurostimulation/neuromodulation, brain-computer interface (BCI), and pharmaceutical neurorestorative therapies, which improved neurological functions and quality of life for patients. Four clinical guidelines or standards of Neurorestoratology were published in 2020. Milestone examples include: 1) a multicenter randomized, double-blind, placebo-controlled study of olfactory ensheathing cell treatment of chronic stroke showed functional improvements; 2) patients after transhumeral amputation experienced increased sensory acuity and had improved effectiveness in work and other activities of daily life using a prosthesis; 3) a patient with amyotrophic lateral sclerosis used a steady-state visual evoked potential (SSVEP)-based BCI to achieve accurate and speedy computer input; 4) a patient with complete chronic spinal cord injury recovered both motor function and touch sensation with a BCI and restored ability to detect objects by touch and several sensorimotor functions. We hope these achievements motivate and encourage other scientists and physicians to increase neurorestorative research and its therapeutic applications.

Key wordsNeurorestoratology      yearbook      pathogenesis      neurorestorative mechanism      therapeutic achievement      guidelines      standards     
Received: 26 February 2021      Published: 17 June 2021
Corresponding Authors: Hongyun Huang     E-mail:
Cite this article:

Hongyun Huang,Lin Chen,Michael Chopp,Wise Young,John Robert Bach,Xijing He,Anna Sarnowaska,Mengzhou Xue,Robert Chunhua Zhao,Ashok Shetty,Dario Siniscalco,Xiaoling Guo,Alireza Khoshnevisan,Ziad Hawamdeh. The 2020 Yearbook of Neurorestoratology. Journal of Neurorestoratology, 2021, 9: 1-12.

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